• BCMB 330: Mechanisms of Development

  3.00 Credits

  The University of Tennessee - Knoxville

  
  A survey course on cellular and molecular basis of embryonic development, differentiation via transcription, RNA processing and translation, sex determination in humans.(RE) Prerequisite(s): Biology 140 and Biology 240.Comment(s): Intended for biology majors in the biochemistry and cellular and molecular biology concentration, but also open to biology majors in other concentrations.
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• BCMB 333: Structural Biol/Human Health

  3.00 Credits

  The University of Tennessee - Knoxville

  
  Structure of biomolecules and structural basis of health-related conditions and pharmaceuticals. Topics include fundamentals and experimental aspects of protein structure and function, medical conditions related to molecular structural variations and structural approaches to drug discovery and drug design. (RE) Prerequisite(s): Biology 160 or equivalent; and Chemistry 130. Comment(s): Intended for biology majors in the biochemistry and cellular and molecular biology concentration, but also open to biology majors in other concentrations.
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• BCMB 401: Biochemistry I

  4.00 Credits

  The University of Tennessee - Knoxville

  
  First semester of a two-course sequence. Covers amino acid and protein structure and chemistry, protein folding, enzyme reactions mechanisms, carbohydrate and lipid structure, function and metabolism, photosynthesis and carbon fixation, membrane biochemistry, thermodynamics of biological systems, vitamins and coenzymes, citric acid cycle and oxidative phosphorylation, and signal transduction.(RE) Prerequisite(s): Chemistry 350.(RE) Corequisite(s): Chemistry 360.Comment(s): Intended for biology majors in BCMB concentration but also open to biology majors in other concentrations.
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• BCMB 402: Biochemistry II

  4.00 Credits

  The University of Tennessee - Knoxville

  
  Second semester of a two-course sequence. Covers membrane lipid metabolism, amino acid metabolism and protein turnover, nitrogen fixation, nucleotide metabolism, nucleic acid structure, integration of metabolism and hormonal signaling, experimental methods of analyzing nucleic acids, DNA replication and repair, chromosome structure and function, RNA and protein synthesis, and control of gene expression.(RE) Prerequisite(s): 401 and Biology 240.
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• BCMB 403: Neurogenetics Laboratory

  3.00 Credits

  The University of Tennessee - Knoxville

  
  Experiments and lectures illustrating methods in modern genetics and neurobiology using model organisms, especially Drosophila or Caenorhabditis elegans.Contact Hour Distribution: Laboratory and lecture.(RE) Prerequisite(s): Biology 240.
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• BCMB 405: Biophysical Chemistry

  4.00 Credits

  The University of Tennessee - Knoxville

  
  Covers (1) thermodynamics; free energy; entropy and enthalpy; chemical equilibrium; solution chemistry; protein folding; DNA melting; protein-ligand association; phase transition; (2) enzymatics; protonation and electron transport. (3) Molecular Structure and Interaction (3a) Theory: Quantum theory, Duality principle, Wave Equation, Single atom model, (3b) Applications: Simulated Molecular Dynamics. Spectroscopy (UV-Vis, Raman, Fluorescence, Circular dichroism, NMR), X-ray diffraction and scattering. (RE) Prerequisite(s): 401 or equivalent. Recommended Background: Calculus. Comment(s): Intended for biology majors in the biochemistry and cellular and molecular biology (BCMB) concentration, but also open to majors in other concentrations.
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• BCMB 409: Perspectives in BCMB

  3.00 Credits

  The University of Tennessee - Knoxville

  
  Current issues in biochemistry, cell biology and molecular biology. Emphasis on current developments and their applications, societal and economic impacts, and moral and ethical implications. An oral presentation and a referenced library-research essay are required. A capstone course. Writing-emphasis course.Satisfies General Education Requirement:(WC)(RE) Prerequisite(s): 311 or 401 or 412.Recommended Background: 9 additional hours of biochemistry and cellular and molecular biology or related courses.Registration Restriction(s): Minimum student level ― senior.
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• BCMB 412: Molecular Biology and Genomics

  4.00 Credits

  The University of Tennessee - Knoxville

  
  Nucleic acids structure and DNA technology. Mechanisms of cell division, replication, transcription, translation, splicing, recombination, DNA repair and transposition, chromosome organization, DNA-protein interaction in gene regulation, genomic imprinting, epigenetics, RNA interference and genome evolution.(RE) Prerequisite(s): Biology 240.Comment(s): Intended for biology majors in BCMB concentration but also open to biology majors in other concentrations. This course satisfies BCMB 402 requirement for biology majors in the BCMB concentration.
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• BCMB 415: Foundations in Neurobiology

  3.00 Credits

  The University of Tennessee - Knoxville

  
  Basic nerve cell physiology, nervous system organization, sensory and motor systems, neural basis of behavior, and nervous system development and plasticity.(RE) Prerequisite(s): Biology 140.Comment(s): It is recommended that students complete Physics 221-222 before enrolling in this course.
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• BCMB 416: Neurobiology Laboratory

  2.00 Credits

  The University of Tennessee - Knoxville

  
  Experiments designed to illustrate concepts of modern neurobiology using electrophysiological, historical, and behavioral neurobiological techniques.(RE) Prerequisite(s): 415 or consent of instructor.
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